Salzmann's corneal degeneration associated with epithelial basement membrane dystrophy.

Salzmann’s corneal nodular degeneration has been defined as a degenerative process that follows episodes of keratitis. The diagnosis is based on the presence of elevated nodules above the surface of the cornea, usually at the periphery. The condition appears commonly associated with a history of scarlet fever, measles, trachoma, vernal keratoconjunctivitis, or phlyctenular keratoconjunctivitis during childhood. A history of ocular trauma, previous surgery, interstitial keratitis, keratoconjunctivitis sicca, and exposure keratopathy is known to be causally correlated with Salzmann’s nodular degeneration. However, it is rarely associated with noninflammatory conditions, such as the corneal dystrophies. We report an uncommon case of bilateral Salzmann’s nodular degeneration associated with corneal epithelial basement membrane dystrophy (CEBMD), which was studied by confocal microscopy.